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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd34039426296d94c2da530240a61cf0c76f5a9a0e1fc4237822224d4999b1e0' 
  AND token = 'qypUC1tQLDCARofRaK7YvUKMiQ8jpUCJeig97wOB6Sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}