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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce61fc6a28b61461172c573bc913f438b4cbd9386abb02ee5acc7df34521647a' 
  AND token = 'eUkFeQMgRSFFyg6V13KFJ2Cn3Y5Spg64OLP48/BzcMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}