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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09075f3669b5a581303b61da018e535c1e99bb01c3073ea6a4f66f03ee64c158' 
  AND token = 'hUFjZJhVeUPw+CTYwDktZNbGF7p9ABhIOfBrj/5IM0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}