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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cd0fb4230ac7264c116385823311cde955a517fc9364efa9f946a388ece0109' 
  AND token = 'WTqwlmRVg9A30Jg2bs6gkXcIaB6gvWWWpma+t6K6W4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}