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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c9b60f81ba6c89e90af457e7a1678927218268f9e672a21bcc3bfce9bbc5c72' 
  AND token = 'ye6FhMHTSMmVIrRAPStQH14PJ1aA1WrA+0x5Yvcb9/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}