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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23d6a50682ad92ac134664d1db1d1d02d4b675397d6d5a09e653e469523cfc76' 
  AND token = 'ezxbQyTQJOFV98vqbGQybGgk0fX6qaWUp5G0N1gyppI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}