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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '766961f4e5a3254e9c27387cfc6271ddddfdb27fd32b8b2bc7ab5ad664df999a' 
  AND token = 'HmJGq/r3znkirjyioCm51xdpFaZWm7fUtbbSHMk0sAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}