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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '421251669050201b3adf2b88242fa23fba2cf8be2a6b634cc107f9d9883d2926' 
  AND token = 'dd45vJT8tdrPHdqa6fhGZQjT34Biab+mTmlZpoIbFqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}