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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e69cc6ba82c96868a9a3a9f7231c14cb0cf22b443ce791f2a55b08bc56c544c' 
  AND token = 'QwiixwgbP6tgOQRUQskC6C8WNb/MUB6oxbIh2OLFuXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}