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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '727484f90a04035164421c7c0b37af9cc06b749d636b5d2ad79f21f892e11afa' 
  AND token = 'aKhkBac38yqpD7mJp5+9IpU39sVB0OTpUhupvHW3+4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}