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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4eb237f2ff9db3edf009c3b46a5bdc7f525ebe3a5e67c0feb6f162896452318' 
  AND token = 'ssm2fp/Ql//XRb5WNZ/FsKD5PVrSkQ2VGMzSljk6MQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}