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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab6ff960fc604be82d15298ca46ed4c1c45165ddc6720aecd71d01aa87eb6e6e' 
  AND token = 'QuJ39dMyXsVhaL2D9SuOS8H67yw0Ls/Cmo9LgCRLHcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}