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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2edf9279a3a7019ad29e7e9742fb837ca5bb8f07c9be40f56a7ef28d8271276' 
  AND token = 'bpbg+ROzZ6jLBgYn4aJTtBUFFMKz96RRL2zUsE1b9lE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}