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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24a1c794bc16ba20402e2938101fcdf8967ce082489f8c361a115639bcf7be3f' 
  AND token = 'e3rC0lmfKB07S4biT/3WqAHefVEolqYHGeBiC3sjCE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}