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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32b303cf8e30f3460c0ccb5494076075288c609e9ec24a442bf0f7a2167e43b1' 
  AND token = 'vSW1uLC0HyLnk8L6m3yLGuI+j4M1PaJbMvGgaV1TzZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}