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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '229c0d321472c146c4682a8945e76424cfe375f1349ec16e2bd263f386544b11' 
  AND token = 'XpHugeslsBN6OT7EheOXqAvQfzof1sPPT+uNIxgDp3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}