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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60d5ddb77f620ecf543604311fa28a3c50a459b19693154a1d3d20ca08c11543' 
  AND token = 'tdC5wa8RckFZ645Eimt+1vf8bhxWF94Xh3T0db0EtiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}