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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c01d477082adbf5a45c17338f749e78bd6ecd629ada12ae6f2717a4d1b6b230' 
  AND token = 'Gw3oiph2jgdt4gmf1kF17kaHr2ShR3/zwEXXfM5FsNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}