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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e3a2468f40a0dcd0f448d99ab912439cbdc9cd754bff55dc4e22031f401e7e' 
  AND token = 'ZzDebiEo3XNORT7jpACLJ1wSnBJLx3RV3MEqZjH2xX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}