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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49889a71c50770377922c370d34ce796e812588ba8338ee89677effedcb210a0' 
  AND token = 'lHKNUYBT754b1UkBXXbyrNQ+5aTSaasyDMUZoYLayAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}