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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b6a7cbbe2362008c5c5bdfe1c3aa8b2e5c752011e58e75616b36b2f374612ca' 
  AND token = 'k0VcZFW9HSaTN64/3XOWI6tbv4yNHdw+FKjSv7ICPGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}