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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd6c514cd9adf0086db59be621d4c998f82395e2cb23c5435765f0d2659e0e33' 
  AND token = 'tO4Z/Ge+oAFPOXV0D5TsTOgDO4z/BRoTMJGMpQtO4yQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}