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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c018449d717c0c5d46032f36cd8220dfbcf30eb8a258b171df234cb70b665941' 
  AND token = '7Wfy+AVLaXQPKqnLtJNuTY9Fkf5RJQQ4y0j1wEd8pMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}