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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49a2e3137d92de9666208c9814a4d1af3a2da081fb614047bc8c442511ab69e5' 
  AND token = 'knCrqMYLOMubNldzbJqmV6TJTYHmSn228a8d7CosC0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}