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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45798bd75850e37daa92b446d7b6e8a6a4abc35d9ae79dc5100d2e6a93ceb5a4' 
  AND token = 'HTMPpednUO1G20qzqTiDqXQeMN9xVVN8KiWxaEajJ7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}