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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a74eb3afe98e40de6b366913a0b592d7d02d3bf8d2bbe987221c76c8253c7c5' 
  AND token = 'dDkJmwXFMvIpkz3cZOt7khz45yKbQc1t7dTA2fDzDiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}