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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '944c704a5d6d5abce3dd36d2adecf26516327b82bc1b97cdc64307d4f91b0339' 
  AND token = 'f0smE8E5m9fnqd2piYNgyAwJhI3WV8fNs8+SCXA7XD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}