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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21f8df01de45e463aefc5053b7a6da9a2a97c9e11289e26d5482f23c0bb5713d' 
  AND token = 'lmH9Y7HRbIFPxlpRApYoPkNcxQKjCS62zNR/JxwYokA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}