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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aea4491723f4e69de72e37a82097eca965ae421447cebfd4cf0a645fe8bfce20' 
  AND token = 'ex1WggFaYGcZgU29O+L7ySBwy2ejTtwujEvn5VfLq4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}