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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cddd76575b25c0f79251fd5ed1016e674d2b6a45f5b3a11685f2776d1f15627a' 
  AND token = 'z2rXPtAh0DQALSe7TN9DGzYHTBb7knMEMb+1pniRhOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}