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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed94e5ff39ad151410888f91877ffb6fac2f9c34d2b1cdeb2da20dc1ed292f0' 
  AND token = 'ftQPyAIxbs+maVjBX15QrKw5YKlEDjqEcGlc5KpHhK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}