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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '491c3dc5ff1d72c93de564c0fea5b5f276631418a888e5d0010762c70ccaa04c' 
  AND token = 'NIdFaGlsVyMOq5at/8AVKAfbAC5t8E9fNllPrxRuLFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}