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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '349127f02ce6329133374f6fe235fce8689a6bbd75d2c2b6532aa9e208c7207b' 
  AND token = 'S8v/zLF3PLCOivf41wqkNAUQNciuc5tK48pEPiZzwso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}