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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '460ce8142b1ad8e62cb74b69235915dc886785dadd1e2ceddfe3d554ae6da543' 
  AND token = 'm1jOsyMHVLnxIMZ4f8naOjDRzeM4t1X1qRxXSRIIUeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}