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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6f21db4f3209ce2d706919ed86f00da7f1c40feff3a9d7817af4db416d14948' 
  AND token = 'v+IRVeJEx1Ic0+TNwgznIUjBgQH3RQFrTvBv11dlgVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}