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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '180535f49ca2fcfcaf9009b5959715d781cfd276ab97ffccb09664e67529aadf' 
  AND token = 'YgPsx/kJJN3PrF3INWaYbDCIbHCHiGV3h/N2Qd3aXw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}