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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d26238346a226bc24f2b5e1d6c643ce43465da8c1178d9c9111dbfef233f08c' 
  AND token = 'dGVLo5PHtPqC+2fC+8BOYskblxN1z4OWMjEFhMSRVTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}