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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec122a928aca0d2ab21af2317ae7f19aad92b022c64f1775ffcd640135a209ec' 
  AND token = 'G8AwSDjb+Wkhq9Zbnq/YeWGeJybhBiUf8vSfQjNf57c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}