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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d855e89cb9ded78097077651bbf1a1e9ddee48a77d89cfa5d3bc015169f52ab' 
  AND token = 'Ec1rpbC1AtIkjau7vL1i2EuMG/cBTU11tlalrzMUSyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}