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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b86b72063eeffba1fbaf32d55f63ab24d0d02e55557417d915079f24ff95174' 
  AND token = 'x/BoiaTqSR5/E6RCRh5pJ0xiHwitPDXt7h3QP4T01zQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}