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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2ccf4d62f2a22ad0d4110f1f51b634a2109836d949559eb56bf8df7f07ba9f3' 
  AND token = '70rZ4IAcdi3dZaUT3Msl8uiLTYnRV013VXCF9/ZVKJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}