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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d491af2c397763bd0dcae2d043ad556270bb6f80164fb3d8e8f0a58aa95a1f9' 
  AND token = 'BM+NBiruzYGmXj43bZymlot+XtEStG2I+pkcgNa1XoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}