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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9f932814c5f4dc024f4470437588239b62d1b485d6bc09a2056a96666090b91' 
  AND token = 'kIYuS3VJylTPE0cd22DnrKiAhkVMEy5UGACZ3/iVfco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}