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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c2b047c2e55208fd5d3cb3ed85fc5ae4986ad1ecf591f249e785248be3ce53b' 
  AND token = 'ohupPnxeEWE06P5ZDpWgqOZ1rx2Ko9J6x586WZN5KII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}