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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '693d179991268c2959e88e73620cfef6a7ecedd28b1a09f0c6998519788f1afc' 
  AND token = 't9SpftSQTs4vXjFWbL4vV1CdHorH7gZQDc/SXB3QQ8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}