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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51b4226a67f18ee68f7ff5cac1c86a2fbb5c9de759cf0ef32eba1382e2da0a1b' 
  AND token = 'pB7X9pN1TbtwcHVqHV5mWm8a3u910G/zPOswNV8yqAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}