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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9cdf4b752ff86c0a56c2cc0ea26bb8631a0f6a05efdeac8fe31d219423d0448' 
  AND token = '2W4B74DTfELdM2+lfvvkoM9xG+jWNfbUxEjTYX2fXmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}