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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8515162c1d138611a0e56dc329858df5317a60e36da392ae4527f2a658dc0af2' 
  AND token = 'U6voz57Io/0WLBDs8XgnamGANnYgbJJ2/GaXbKLloPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}