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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2e194686fd2c4848999980aa353ef62bff0f0a16346b182676d9d0cd6bfc8ae' 
  AND token = '2zDom2TmGPl7nDfBMnuU2RBeWD3IJm0k3ZMBzi9akHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}