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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f6c5eede54df9e99229fce4fa13e540c7c17bb3e3c19a2ca409aec98867ba0c' 
  AND token = 'tYnQ2KYRZUh5PQVcDXonWn+cHHE6h2WeQTrXecVg+fQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}